I wanted to reply to your letter, but I can’t come at it anywhere.(我想回复你的信,但哪里也找不着了。)这里come at something表示找到什么东西。也可以表示发现什么,得到什么。如
It is always difficult to come at the truth.(得到真相往往很困难。)
The shrew came at her husband with a rolling-pin.(母老虎用擀面杖打她老公。)这里come at someone表示攻击某人。